الفهرس | Only 14 pages are availabe for public view |
Abstract Malnutrition and inflammation are more common in end -stage renal disease patients on maintenance hemodialysis. Malnutrition in patients on hemodialysis due to inadequate nutritional intake occurs due to anorexia, gastropathy and enteropathy, inflammation and/or infection, medications, psychosocial factors, increase requirements due to dialysis-related nutrient losses, alterations in protein metabolism, metabolic acidosis, and inflammation. In response to inflammation adipose tissue releases pro-inflammatory mediators and adipokines in circulation that involved in various metabolic and pathologic processes. Adipose triglyceride lipase (ATGL) is Novel adipokines with proposed desirable effects on inflammation, and lipids and glucose metabolism. Nutritional status of hemodialysis patients should be assessed with valid measures assessment of nutritional status include dietary intake assessment, anthropometry, serum proteins and cholesterol, urea and creatinine kinetic, body composition measurements using malnutrition inflammation score MIS a low cost and simple tool in assessment of malnutrition. Nutritional screening is important for detection of malnourished patients or who at risk of malnutrition and help in preventing and management of malnutrition. Management of malnutrition in patients on maintenance hemodialysis help to maintain healthy weight, promote growth and development, ensure adequate intake of macro- and micro-nutrients, and avoid metabolic imbalances or development of mineral bone disease (MBD). The long-term goal is to reduce the risk of chronic morbidity and mortality. |