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Abstract Catheter-related bloodstream infection (CRBSI) is defined as the presence of bacteremia originating from an intravenous catheter. It is one of the most frequent & lethal complications of central venous catheterization bacteremia . Sepsis is defined as a complex syndrome, which results from a serious infection followed by inflammatory response, Regulatory T cells play an important role in suppression of immune response. The aim of this study was to evaluate the potential role of regulatory T cells CD4+CD25+CD39+Tregs in the diagnosis of CRBSI in patients with central venous catheter. Patients included 2 groups:Sepsis group&Control group. Sepsis group when compared to control group had longer catheter indwelling time. Sepsis group when compared to control group had significantly higher symptoms and signs of infection, Sepsis group when compared to control group had significantly higher CRP value. Sepsis group when compared to control group had significantly higher CD4+CD25+CD39+percentage and absolute count level. |