الفهرس 
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Abstract
The aim of our study was to evaluate the efficacy and safety of medical treatment of undisturbed ectopic pregnancy either by Methotrexate, or by Aromatase inhibitors ”Letrozole” in comparison to laparoscopic treatment for the same purpose in well selected cases of undisturbed ectopic pregnancy at Minia Maternity University Hospital during period from January 2018 to December 2018.
This study included thirty four patients of undisturbed ectopic pregnancy randomized in to three groups, ten cases cases underwent laparoscopic salpingostomy, another ten cases received single dose of methotrexate (1 mg/kg IM) and the remaining cases received Letrozole 2.5mg, in combination with Norethisterone 5 mg as an adjuvant therapy for 10 days both twice daily.
Laparoscopy remains the gold standard first line modality for diagnosis and treatment of undisturbed ectopic pregnancy. It is also the modality of choice in case of failure of medical treatment.
Medical treatment with methotrexate for undisturbed ectopic pregnancy has its definite role as an alternative to laparoscopy.
Letrozole has the advantage of easy administration and high safety profile when compared to methotrexate and laparoscopy.
We recommend further & bigger studies on the use of letrozole in treatment of undisturbed ectopic pregnancy to establish its role.
We recommend further studies on the use of letrozole as an adjuvant treatment With Methotrexate or laparoscopy.