الفهرس | Only 14 pages are availabe for public view |
Abstract Bilirubin has traditionally been considered a cytotoxic waste product. However, recent studies have shown bilirubin to have anti-oxidant, anti-inflammatory, vasodilatory, anti-apoptotic and anti-proliferative functions. Cross-sectional studies have demonstrated negative associations between serum bilirubin and metabolic syndrome (MetS), diabetes and atherosclerotic cardiovascular diseases (CVDs). However, longitudinal studies show conflicting results. Serum bilirubin levels are determined both genetically and environmentally, and fluctuate throughout one‘s life. Longitudinal data suggest that some genetically hyperbilirubinemia individuals may have a lower CVD risk than the general population. The aim of work of this study was to evaluate the relationship between TB IRA flow as confirmed by angiography before receiving PCI and the prognostic role of high TB levels on in-hospital major adverse cardiac events (MACE) in patients with STEMI undergoing primary coronary intervention (PCI). |