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العنوان
Comparative study of day three thawed embryo transfer versus day five transfer after extended culture/
المؤلف
Abdel Hamid, Ahmed Mahmoud Fawzy.
هيئة الاعداد
باحث / أحمد محمود فوزي عبد الحميد
مناقش / محمد محمد إبراهيم خليل
مناقش / أشرف هاني عبد الرحمن
مشرف / أشرف هاني عبد الرحمن
الموضوع
Obstetrics. Gynecology.
تاريخ النشر
2019.
عدد الصفحات
38 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
22/10/2019
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Obstetrics and Gynecology
الفهرس
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Abstract

Embryos are typically transferred to the uterus in either the day 3 zygote or day 5 blastocyst stages when certain criteria are met. In theory, allowing day 3 embryos to mature for two additional days allows for self-selection of the “best-quality” embryos, resulting in fewer embryos transferred, higher implantation rates, and decreased HOM rates. Existing studies have shown varied results. While most have shown similar implantation and pregnancy rates, the impact on (HOM) gestations remains unclear. Ultimately, the answers to these clinically relevant issues will help providers accurately counsel couples as to the optimal day of transfer.
The aim of the current study was to compare the results of day 3 embryo transfer versus day 5 embryo transfer regarding rate of chemical pregnancy, clinical pregnancy and implantation rate.
For that purpose two groups of patients were included in the study. The first group included patients whose embryos transfered in day 3 and the second group included patients whose embryos were transferred in day 5.
Results showed that there were no significant statistical differences between the two groups as regards to basic data and demographic data including age and comorbidities.
The first finding of the current study was that the group with day 3 transferred embryo had a 53.3% implantation percentage embryos of 4 while the mean the percentage of implanted embryos in the day 5 group was only 76.7% . That means that the day 5 technique had higher implantation rate but the difference was not statistically significant.
With respect to chemical pregnancy, although there was an increasing in chemical pregnancy rate in day 5 method more than day three method, there was no significant difference between the two groups regarding the incidence of chemical pregnancy which was 47% and 66% respectively. The rate of clinical pregnancy also was comparable in both methods (33% in day three group versus 53% in day five group) without significant statistical differences. Moreover, The ongoing pregnancy percentage in day three method was (30.0%) and in day five method was (46.7%). Again, there were no significant statistical differences between the two methods as regards to percentage of ongoing pregnancy.