الفهرس 
1. INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Liver diseases are among the most serious aliment. They may be classified
as acute or chronic hepatitis (Inflammatory Liver Diseases), hepatitis (Non-
Inflammatory Diseases) and cirrhosis (degenerative disorder resulting in fibrosis
of the liver) .
Carbon tetrachloride (CCl4) has been widely used in animal models to
investigate chemical toxin-induced liver damage.The most remarkable
pathological characteristics of CCl4 inducedCirrhosis are fatty liver, cirrhosis and
necrosis .
Phototherapy is the treatment and prevention of diseases using plants or
plants part, such as leaves, flowers, roots, fruits, seeds, and rhizomes. Preparation
made from them called medicinal plants, or herbs. Many plants were suggested
to ameliorate or care the liver diseases, among them were the chia. Medicinal
plants have very important place as they not only maintain the health and vitality
of human beings and animals, but also cure several disease, including liver
disorders without causing any toxicity .
The present study investigated the effects of chia seeds on CCl4 induced
Cirrhosis in rats . Thirty male albino rats were divided into (5) groups )6) rats in
each group. Two groups were controls, one fed on basal diet only as a negative
control and the other one fed on basal diet after injection with CCl4 as a positive
control. The other groups were injected by CCl4 then received basal diet
containing chia seeds at the levels of 2.5, 5 and 10 % . Liver damage was
assessed by estimation of serm concentration of enzymes activities of aspartate
amino transferase (AST), alanine amino transferase (ALT), lipid fraction (total
cholesterol and triglyceride), cholesterol fraction (HDL-c, LDL-c, VLDL-c),
Uric acid, Urea nitrogen and glucose. Results showed an improvement in case of
tested seeds at the level of 5% followed by the level of 10% for the above
parameters. So, this study concluded that CCl4 induced liver damage in rats can
be ameliorated by administration of 5% chia seeds.