الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 118 |  |  |
| | | from | 118 | | |
Abstract
Epilepsy is a common neurological problem in children. Fifty million people have epilepsy globally; 20 % of them are children. Problem is further compounded in developing countries as they add on 80 % of 3.5 million new cases of epilepsy. Epileptic seizures affect 1–2 % of the population and 4 % of children. Developing countries have higher prevalence due to poor peri-natal care and higher incidence of neuro-infections, injury and poor nutrition.(Sharma, 2013) Epilepsy in children is due to a diverse group of etiologies. Many children have a specific electro clinical syndrome .Such syndromes denote specific clinical seizure types, EEG findings, characteristic clinical features (eg, age at onset and associated neurologic and psychological findings), and underlying pathophysiologic or genetic mechanisms. Identifying the underlying cause of epilepsy or specific electro clinical syndrome is critical to understanding its natural history and best treatment options.(Wirrell, 2016) Drug-resistant epilepsy is defined as the “failure of adequate trials of two tolerated, appropriately chosen and used antiepileptic drug schedules (whether as monotherapies or in combination) to achieve sustained seizure freedom.” Drug-resistant epilepsy affects about one-third of people living with epilepsy. Patients with epilepsy have worse quality of life, family function, and social support compared to other patients who are chronically ill. Furthermore, Patients with drug-resistant epilepsy face an increased risk of sudden unexpected death in epilepsy (SUDEP).(Harden, & Louis, 2019)