الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 23 |  |  |
| | | from | 23 | | |
Abstract
Diabetes and cardiovascular diseases often appear as two sides of a coin. Coronary artery diseases (CAD) constitute a major health problem in many parts of the world and are an important cause of morbidity and mortality. It is predicted that by the year 2020, CAD will be the main cause of disability worldwide. Moreover, Peripheral arterial disease (PAD) in diabetic patients is a manifestation of atherosclerosis characterized by atherosclerotic occlusive disease of the lower extremities and is a marker for athero-thrombotic disease in other vascular beds.
This cross sectional study was conducted in Cardiac catheterization unit, Cardiology department, Suez Canal University Hospital, Ismailia, Egypt, to assess the potential relation between ankle brachial index and pulse pressure to the severity of coronary and peripheral arterial diseases in diabetic patients as well as to assess asymptomatic peripheral vascular disease in coronary artery disease diabetic patients.
The study aimed to assess the relation between ABI and PP as predictors of the severity of CAD and PAD assessed by GENSSENI score and TASC classification as bedside noninvasive method.
Certain associated risk factors were studied; smoking and hypertension. As well as distribution of types of diabetes mellitus were studied. Among the studied patients, 54% were smokers and 79% were hypertensive. Type II was represented in 90% of the studied patients, while 10% were type I.
The diagnostic criteria for PAD based on ABI are interpreted as follows: Normal if 0.91-1.30, Mild obstruction if 0.70-0.90, Moderate obstruction if 0.40-0.69, Severe obstruction if < 0.40 and poorly compressible if >1.30. The majority of the studied patients (39%) had mild obstruction then 32% had moderate obstruction while 8% Poorly compressible and 5% Severe obstruction, with only 16% normal. Pulse Pressure was assessed if normal or wide. It was normal in 86% of the studied patients.
PAD was assessed and classified according to TASC classification into 3 levels: A, B and C. The majority of the studied patients (58%) were classified as A then 36% classified B while the rest 6% were c. Gensini score was of average 58.7 ± 28.7 with minimum score was 10 and maximum score was 110, as shown in table (3). Then, cases were categorized according to their Gensini score.