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Abstract Lower respiratory tract Infections continues to threaten the health of children worldwide. Identification and triage of seriously ill patients visiting emergency department is very important for prioritization of care. Presence of simple guidelines for the emergency care of sick children would aim to improve the triage and initiation of appropriate emergency treatment. The study aimed to assess of “TOPRS” clinical scoring system in determination of severity of lower respiratory tract infection and to detect any association between platelet count at time of hospitalization and the severity of infection. The present study is a prospective study conducted in Assuit university children hospital during the period from November 2017 to February 2018. 100 infants and children aged one month – 2 years old were included in our study. Results: Significant relationship between outcome of the selected cases and different variables of TOPRS clinical score, which indicates that TOPRS score can predict outcome in patients with pneumonia. Highest mortality rate was detected in score 6 with 100% of cases and lowest mortality ratio was detected in score 2 with 17.39% which indicates that increase in the number of abnormal physical variables caused a statistically significant increase in the mortality Significant relationship between outcome and some of WHO criteria (nasal flaring, chest indrawing, convulsions). This means presence of these signs in cases with pneumonia has poor outcome. 75% of cases with thrombocytosis at admission were admitted for 6-10 days, 25% admitted for more than 10 days while 0 cases stayed for 3-5 days which indicate increasing period of hospitalization in those who had thrombocytopenia. 66.7 % of cases stayed for 3-5 days at hospital, 33.3% of cases stayed for 6-10 days and 0% cases stayed for more than 10 days which indicate decreasing period of hospitalization for those who had thrombocytopenia and this may be due to high death rate that shortens the hospital stay. 25% of cases with thrombocytosis at admission were died in hospital while 100% of all cases having thrombocytopenia at admission were died. This means that thrombocytopenia is related to poor outcome than thrombocytosis. |