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Abstract Introduction: Large scale disasters around the world demonstrate that no one and no country is immune from the threat of natural or other tragedies. Disasters occur every day somewhere in the world with dramatic impact on individuals, families and communities. The first decade of the twenty first century had considerably raised an awareness of the potential danger to modern civilization from disasters, both natural and manmade. Aim of the study: This study aimed assess emergency nurses’ knowledge and practice regarding preparedness of disaster management. Subject and methods : A descriptive research design was utilized in the current study, in the emergency department at Mansoura emergency hospital on 22 emergency nurses. Two tools were used, first tool was a disaster structured questionnaire which contains two parts Part 1 was about nurses’ demographic data and part 2 was about disaster nurse’s knowledge questionnaire, second tool was about disaster nursing performance observational checklist. Results : Statistical analysis demonstrated that below three forth (72.7%) of nurses revealed un satisfactory level of knowledge regarding preparedness of disaster management with the mean knowledge score 10.32 ± 2.75 out of 15 score, statistical significant relationships were found on nurses regarding knowledge about preparedness of disaster management and experience in the emergency department, as well as attending previous courses related to disaster preparedness & total practice score regarding preparedness of disaster management among the studied emergency nurses consider satisfactory regarding patient’s admission and consider unsatisfactory regarding triage of care, personal protective equipment and infection control measures. Conclusion: It can be concluded that the level of knowledge and practice was un satisfactory regarding preparedness of disaster management and also the study finding showed that significant difference between nureses’ knowledge regarding preparedness of disaster management and duration of experience in emergency department , moreover there was significant difference between nureses’ knowledge regarding preparedness of disaster management and attending previous courses related to disaster preparedness. Recommendations: Integration of clearly titled theory and practice, teaching courses about disaster and emergency preparedness into nursing curricula are crucial needed and provided in respect to their training preferences. |