الفهرس 
Pathophysiology of Aortic Valve StenosisOnly 14 pages are availabe for public view
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Abstract
Transcatheter aortic valve implantation (TAVI) has established its effectiveness as a substitute to conventional surgery in patients with high grade aortic valve stenosis who have high cardiovascular surgery risk score. Doppler imaging and 2D speckle tracking analysis are highly sensitive markers for regional and global LV systolic function. Longitudinal strain (LS) is considered as the most robust myocardial strain component. Previous studies found that the transcatheter aortic valve replacement was associated with better ejection fraction and reverse remodeling but with higher incidence of aortic regurgitation than the surgical procedure. Upon review of echo-cardiographic findings after TAVI, there was a statistically significant differences in left ventricular diastolic diameter, ejection fraction, global longitudinal strain, global circumferential strain, and global radial strain measures. Our results come in accordance with results retrieved from many published studies in diverse populations. Our Study Showed a highly significant positive correlation between inter-ventricular septum diameter in diastole and left ventricular posterior wall thickness at end of diastole. Also, between left ventricular diastolic diameter and ejection fraction as well as left ventricular systolic diameter. Our data showed a significant positive correlation after TAVI between global circumferential strain and global radial strain. Ejection fraction was correlated positively with global radial strain as well as global longitudinal strain after TAVI.