الفهرس 
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Abstract
Background : Sepsis remains an important source of morbidity and mortality among neonates (Wynn, 2016). Blood culture is the current gold standard used for diagnosis of neonatal sepsis, but it has many disadvantages like it can be inaccurate and the time required confirming results may take up to three days (Paolucciet al., 2012), thus besidesthe nonspecific clinical manifestations of sepsis in neonates and the absence of sufficiently accurate biomarkers can contribute to delay in the diagnosis and introduction of treatment (Arcagok and Karabulut, 2019). Therefore, more convenient, sensitive and specific marker is needed for diagnosis of bloodstream infections. CD64 expression on neutrophils has shown particular promise as an early marker for sepsis(Choo et al., 2012). CD64 is Fc receptor of high affinity expressed on neutrophil’s surface, this expression increases when neutrophils are activated by infectious stimuli (Yehet al., 2019).