الفهرس 
ThalassemiasOnly 14 pages are availabe for public view
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Abstract
Thalassemias are inherited hemolytic disorder of hemoglobin synthesis. It was common in the (Mediterranean region), the Far East and South America. It is characterized by; various degrees of defective (β-chain) production; an imbalance in (α/β-globin) chain synthesis, ineffective erythropoiesis and anemia. (β-thalassemia)minor is clinically silent, with mild hypochromic and microcytic anemia, while β-thalassemia major is characterized by severe anemia and requires regular blood transfusions and chelation therapy for survival (Cao and Galanello., 2010).The aim of this study was assessment of some procoagulant factors in (β -thalassemic) children and risk of thrombosis.This study was carried out on (40) β -thalassemic children selected from the outpatient and inpatient at clinics of Pediatric Hematology department of Tanta University Hospitals.Forty apparently healthy children matched in age and sex was used as controls.All patients were subjected to the following 1-Complete history taking.2- Thorough clinical examination.3-Laboratory investigations