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Abstract Autism spectrum disorder is a neurodevelopmental disorder with a complex interaction between genetic and environmental risk factors. It is characterized by social interaction impairment, repetitive behaviour and sensory abnormalities. Its prevalence is increasing recently where higher numbers of children with ASD are accessing health care systems. It is one important cause of childhood disability with significant burden on parents and society. The assessment and management of ASD is complex. Thus, requiring continuous efforts for developing evidence-based guidelines for the screening, diagnosis, and treatment of autism spectrum disorder. Sensory processing abnormalities have been reported in 42% to 88% of children with the disorder. Atypical sensory features are thought to result from aberrant sensory processing, and may be evident across all sensory modalities, including auditory, tactile, vestibular, oral, olfactory, movement and visual domains. Subjects with autism spectrum disorder have difficulties in communicating their emotional states; however, several studies have shown a high prevalence of anxiety in those subjects. The relation between abnormal sensory profile, repetitive behavior and anxiety symptoms in children with ASD remain to be elucidated. Therefore, this study was done to clarify such relation in Egyptian children with autism spectrum disorder. Our study aimed at studying the sensory profile in autistic children and to study its relation to both repetitive behavior, a core feature in ASD, and anxiety symptoms. The study included 60 children diagnosed with autism spectrum disorder according to DSM-5 among those attending the Child and Adolescent outpatient clinic at Elhadara Hospital, Alexandria University and Mamoura Psychiatric Hospital. Those with hearing or visual impairment, epileptic syndromes, psychotic illness or other affective disorder were excluded from the study. Fifty-three boys (88.3%) and 7 girls (11.7%) shared in this study. Their mean age ±SD was 6.41 ± 1.99 years. |