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العنوان
Effects of green tea extract on fertility in rats /
المؤلف
Barghout, Basma EL-Desoky EL-Desoky.
هيئة الاعداد
باحث / بسمة الدسوقي الدسوقي برغوث
مشرف / السعيد الشربيني السعيد
مشرف / شيماء عبدالسلام السيد
مناقش / عبدالعزيز فتوح عبدالعزيز
مناقش / جهاد رمضان السيد
الموضوع
Green tea - Therapeutic use. Green tea - Extract. Rats - Fertility.
تاريخ النشر
2020.
عدد الصفحات
online resource (180 pages) :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Small Animals
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة المنصورة - كلية الطب البيطرى - Biochemistry and Chemistry of Nutrition
الفهرس
Only 14 pages are availabe for public view

from 180

from 180

Abstract

Green tea (Camellia sinensis) extract can reduce the tissue damage caused by toxins due to its antioxidant. properties.In the present study, 60 male Westar rats were randomly divided into 6 groups group 1 (control group), group 2 (vitamin C group), group 3 (green tea extract group ( GTE ) ,group 4 (cadmium chloride group ), group 5 (vitamin C + Cd group) ,group 6( GTE + Cd group ) .After 30days, the testes of rats were taken for biochemical analysis of Catalase activity (CAT),Reduced. Glutathione level (GSH), Nitric Oxide activity (NO) and Malondialdehyde level (MDA).testosterone , FSH and LH levels as well as SYBR Green real time PCR for17-beta hydroxysteroid dehydrogenase III (17B.HSDIII). (Cd) toxicity decrease ant oxidative status of testes, Testosterone, FSH and LH levels while increase lipid peroxidation and NO level. (GTE) and (VitC) increased the activity of (CAT), level of (GSH) and (17beta HSDIII), while the level of (MDA) and (NO) were decreased compared to control. Conclusion: Green tea has an antioxidant effect that reduces the effects of free oxygen radicals produced from toxins such as cadmium chloride. In addition, it could decrease lipid peroxidation of the cell membrane and ultimately prevent the destruction of testes tissues. Key words: Infertility, Cadmium, Green tea extract, 17beta.H.