الفهرس | Only 14 pages are availabe for public view |
Abstract Background Cardiac arrythmias are expected among patients with epilepsy, because of the effect of the antiepileptics. Temporal lobe epilepsy also causes autonomic seizures that may affect heart rhythm Aim of the Study: This work was carried out to assess QT interval prolongation in epilepsy and whether there’s a difference in QT interval prolongation between temporal epilepsy and non-temporal epilepsy. Subjects and Methods: This study was conducted on 100 patients, 50 aged and sex matched healthy controls who underwent a prolonged (6 to 24 hours) 22 channel computerized EEG monitor with 10-20 system electrode placement and 12 lead electrocardiogram (25 millisecond speed). QT, QTd and QTc using Bazzet’s formulae were calculated. Results: The results showed statistically significant prolongation of QTd and QTc in epilepsy patients when compared to that of age and sex matched control. Conclusion: Significant prolongation of QT interval in epilepsy patients (11% suffered pathological prolonged QT). Marked prolongation of QTc and QTd in temporal lobe epilepsy over non temporal group. Presence of other factors like seizure control and presence of epileptogenic discharge on latest EEG that cause prolongation of QTc. |