الفهرس 
EndometriosisOnly 14 pages are availabe for public view
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Abstract
Background: Endometriosis is defined as the presence of endometrial-like tissue outside the uterine cavity, it is a common, chronic, progressive and inflammatory disease, associated with local and systemic altered immune system.
Objective: This work aims to study the PCR genetic expression of interleukin 37 in the eutopic and ectopic endometrium of women with endometriosis in comparison with controls.
Methodology: This study was conducted in Ain Shams University Maternity Hospital in laparoscopy department. Studied the association between expression of interleukin 37 in the eutopic and ectopic endometrium of women with endometriosis in comparison with controls. The PCR genetic expression of interleukin 37 was performed in the clinical and chemical pathology department. The study was performed form October 2016 to June 2018.
Results: The current study found that no statistically significant differences between both groups regarding age, parity and indication for laparoscopy. where the current study found statistically significant differences regarding normalized target gene expression levels (2-ΔΔCT) in eutopic endometrial tissues of the endometriosis and control groups with rang 8.50 – 45.60 and 0.33 – 11,38 respectively, mean ± SD 20.78 ± 10.32 and 5.40 ± 2.94 respectively and 95% confidence interval16.21 -25.36, and 4.12 – 6.67 respectively with P value <0.001.
Conclusion: The study found statistically significant differences regarding normalized target gene expression levels (2-ΔΔCT) in intraperitoneal fluid of the endometriosis and control groups with 95% confidence interval 25.81 – 38.52and 8.97 – 12.7 respectively with (P <0.001).