الفهرس 
List of contentsOnly 14 pages are availabe for public view
 |  | from | 67 |  |  |
| | | from | 67 | | |
Abstract
LUTS may persist in a proportion of patients after transurethral prostatectomy and this could be attributed to UTI. However, urinalysis alterations including pyuria are common after transurethral prostatectomy. This is not always a pathological finding and does not mean necessarily that there is an infection. Presence of pyuria postoperatively can lead to unnecessary diagnostic measures as well as medical treatment. In this trial, we aimed to evaluate the natural history of post transurethral prostatectomy pyuria and its clinical correlations to different functional urinary outcome measures. Methods : Between March 2018 and February 2019, 187 patients who had BPH underwent transurethral prostatectomy via resection, vaporization, enucleation and incision in 96 (51.3%), 27 (14.4%), 38 (20.3%) and 26 (13.9%) patients respectively. Patients were evaluated preoperatively, before discharge and postoperatively at 2, 4, 8, 12 and 24 weeks by urinalysis. Pyuria was identified as urine WBCs > 5/HPF. Urine cultures were done routinely preoperatively, before discharge, at 4 weeks and at 12 weeks follow up points. Antibiotics were given only to patients with positive urine cultures. Urinary symptoms were evaluated by IPSS, QOL, dysuria visual analogue scale, uroflowmetry and PVR preoperatively and at different follow up points. Results : Only 152 patients have completed follow up and were available for final analysis. All functional urinary outcome measures showed statistically significant improvement at all follow up points. At 24 weeks, 80 patients (52.6%) had persistent pyuria. 5 patients (6.3%) had +ve urine cultures at 12 weeks. This showed statistically significant difference (P = 0.031). 13 patients (16.3%) were diabetic. This also showed statistically significant difference (P = 0.036). Multivariate analysis showed that DM is an independent predictor of persistent pyuria at 24 weeks [OR = 2.310, 95% CI = (1.043 – 5.117), P = 0.039]. On the other hand, the persistence of pyuria at 24 weeks did not show any statistically significant correlation with all functional urinary outcome measures. Conclusions : Pyuria is expected to be found in the majority of patients after transurethral prostatectomy, however it resolves nearly in half of them with time. Presence of DM and positive urine culture at 12 weeks are predictors for the persistence of pyuria at 24 weeks and DM is found to be an independent predictor. However, 24 weeks persistent pyuria does not have any statistically significant correlation with different functional urinary outcome measures.