الفهرس 
Hyperemesis gravidarum (HEG)Only 14 pages are availabe for public view
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Abstract
Hyperemesis gravidarum is characterized by persistent nausea and vomiting associated with ketosis and weight loss (>5% of prepregnancy weight). Hyperemesis gravidarum may cause volume depletion, electrolytes and acid-base imbalances, nutritional deficiencies and even death. Hyperemesis requiring hospital admission occurs in 0.3-2% of pregnancies.
The exact cause of hyperemesis gravidarum is unknown but there are some hypothesis like hormonal mechanisms, emotional factors and H. pylori infection. The increased serum level of steroids and human chorionic gonadotrophin hCG cause change in pH of gastrointestinal tract, beside the pregnancy induced gastrointestinal tract dysmotility and altered humoral and cell mediated immunity in pregnancy, all favor activation of H. pylori infection.
The relationship between helicobacter pylori and hyperemsis gravidarum is not fully understood with a lot of debate.
Positive association between HEG and H.pylori infection has been demonstrated by several case control studies.In contrast, some studies found no relationship between HEG and H. pylori.
Helicobacter pylori is one of the commonest bacterial infection worldwide and accepted as the cause of chronic active gastritis.Most patients continue through life with a chronic superficial gastritis while some develop either duodenal or gastric ulcer.
Our study was conducted on 100 pregnant women at 6-14 weeks of gestation, 50 women with hyperemesis gravidarum and 50 women not suffering from Hyperemesis gravidarum