الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Coronary syndromes without ST elevation are a heterogeneous disorder ranging from stable angina (SA) without evidence of myocardial necrosis to non ST elevation myocardial infarction acute coronary syndrome (NSTE-ACS). Because of different clinical presentations, coronary syndromes without ST elevation encompass a wide range of events and have different prognostic values in relation to the type of plaque lesions and the spread of coronary atherosclerosis.
The number of critical occlusion of coronary vessels in patients with coronary artery disease (CAD) is considered an important prognostic factor. Current research does not reach to definite association between the number of occluded vessels and specific circulatory biomarkers.
Myocardial necrosis is characterized by loss of contractile tissue and changes of ventricular geometry and this would be anticipated to modify the function of heart muscle. The transthoracic echocardiographic examination is the most popular method for non-invasive detection of LV function and risk stratification after acute coronary syndromes (ACS). Numerous studies have demonstrated that ejection fraction (EF) or other closely related parameters are powerful guides to predict the risk of future events.
N-terminal-pro-brain natriuretic peptide (NT-proBNP) is secreted in response to cardiac hemodynamic stress mediated by volume and pressure overload. NT-proBNP is very stable at room temperature and is often measured in clinical practices, especially in the emergency department. NT-proBNP has been proposed to provide prognostic information in patients with acute coronary syndrome (ACS).
BNP and proBNP could be indicators for multivessel disease, poor TIMI flow, as well as markers of coronary disease extension.
The aim of our study was to assess, the relation between N-terminal pro brain natriuretic peptide and the severity of coronary artery disease in patients with non ST elevation acute coronary syndrome (NSTE-ACS).