الفهرس 
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Abstract
Materials and Methods: The study included 24 patients with pathologically proven cancer rectum and who were subjected to neoadjuvant chemo-radiotherapy. Each patient was imaged twice on an MRI machine; a base line pre neoadjuvant treatment and 8 weeks after finishing the neoadjuvant treatment. Conventional sequences were viewed first to identify the lesion and measure its size (craniocaudal dimension) then DWI images were viewed. The ADC parameter was calculated. Results were compared before and after neoadjuvant therapy.
Results:The ADC values before and after NACT were significantly higher in the responder group, suggesting that ADC values might be useful in assessing the good response before surgery. In addition, the percentage changes in ADC values before and after NACT showed the highest diagnostic performance.
Conclusion: In conclusion, the present study demonstrates that adding DW MR imaging to conventional MR imaging yields better diagnostic accuracy than use of conventional MR imaging alone in the evaluation of treatment response to neoadjuvant CRT in patients with locally advanced rectal cancer.