الفهرس 
Anatomy of The SkinOnly 14 pages are availabe for public view
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Abstract
Severe burns in the pediatric population are associated with high mortality and morbidity in any developing countries.
The aim of this work was to assess the role of homograft in management of major partial thickness burn in children and its effect on general condition and locally on the wound.
Traditionally, partial-thickness burns have been treated with topical antimicrobial agents during twice daily dressing changes until the eschar separated (8).
The traditional approach leaves the burn wound open for long periods, increasing the potential for wound infection and exposes patients to the pain of daily cleaning and dressing changes.
In response to a burn injury, an inflammatory response occurs which is characterized by the release of catecholamines, vasoactive mediators, and inflammatory markers which can trigger the onset of systemic inflammatory release syndrome (SIRS).
MODS exists in a continuum with the systemic inflammatory response syndrome (SIRS) which affects most patients with a severe burn, with or without an infection.
Hypothermia is a continued high risk in child population due to the high surface-to-volume ratio and low fat mass. Hypothermia can increase the depth of the burn.
Management of acute burn: following the abcds protocols for the first aid.
Fluid resuscitation
Pain control
Local wound management
Special considerations for special types of burn eg. Electirical burn
Wound coverage with autografts or biologic or synthetic skin substitutes
In our study we used the homograft as askin substitute for coverage of major partial thikness burn wound in childrens with burn of 20% TBSA or more of TBSA, the homograft is acquired from parents through mini abdominoplasty or other surgical procedures.
Our results show that early excision of burn wound and coverage with homograft reduced the TBSA, rate of infection, number of dressing changes, pain and also decreased length of hospital stay.