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Abstract Abstract Introduction: Ambulatory blood pressure monitoring (ABPM) is now considered the gold standard for diagnosing hypertension among hemodialysis (HD) patients. Abnormal vascular regulation of intravascular fluid leads to chronic volume overload in children with end-stage renal disease (ESRD). The non-pharmacologic management of hypertension stresses mainly on the management of dry weight. The aim of the study was to evaluate the impact of ABPM and bioimpedance analysis (BIA) on the control of hypertension among pediatric HD patients. Patients and methods: this prospective observational study was carried out at the Pediatric Dialysis Unit, Children’s Hospital, Ain Shams University during the period from November 2017 till November 2019. All patients involved were subjected to an increase in ultrafiltration (UF) volume over their HD sessions for 4-6 weeks. The blood pressure and volume overload were measured by ABPM and BIA initially to categorize patients according to their BP states and at the end to evaluate the response. Results: The results revealed that ABPM identified previously unknown hypertensive patients. Moreover, with the aid of BIA the final volume overload (VO) values had been lowered compared to their initial values with a highly significant difference. In conclusion, the efficiency of ABPM and BIA in evaluating and managing blood pressure among children on regular hemodialysis proved to be effective and essential |