الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Cardiac involvement in diabetes commonly manifest as coronary artery disease (CAD) and less commonly as diabetic cardiomyopathy and cardiac autonomic neuropathy. CAD alone accounts for the major chunk of mortality in diabetes. Accelerated and greater frequency of CAD has been widely documented in hospital, autopsy, and epidemiological as well as longitudinal studies in several populations. The SYNTAX score (SX score) is a comprehensive angiographic scoring system that is derived entirely from the coronary anatomy and lesion characteristics. Aim of the work: The main aim of this study was to evaluate prospectively detailed angiographic coronary findings by using the SYNTAX score among diabetic and non-diabetic patients with recent history of CCU admission due to ACS and undergoing elective coronary angiography at Mansoura Specialized Medical Hospital. Methodology: This is a prospective observational study that enrolled 100 patients with Acute Coronary Syndrome among which 50 patients who are diabetic and other 50 patients who are non-diabetic to evaluate prospectively detailed angiographic coronary findings among patients undergoing elective coronary angiography at Mansoura Specialized Medical Hospital. The mean age for DM group was 58.08±8.06 years and the mean age for control group was 56.40±8.66 years. DM group included 31 males (63.3%) and 18 females (36.7%), while control group included 40 males (80%) and 10 females (20%). Results: The majority of DM group was treated by insulin (60%), while the rest were treated by either oral treatment (34%), or combined therapy (6%). HTN was significantly more prevalent among DM group than controls, while prevalence of smoking and dyslipidemia weren’t different to the level of statistical significance. Regarding SYNTAX score, diabetic patients had significantly higher scores than non-diabetics. While on categorization of the results, the prevalence of low or intermediate SYNTAX score wasn’t significantly different between both groups. Conclusion: Based on the results of the current study, it can be concluded that Type 2 diabetes has a significant adverse effect on the anatomy of coronary arteries, causing more multivessel and extensive coronary artery disease as well as higher SYNTAX score than in non-diabetic patients.