الفهرس 
PreeclampsiaOnly 14 pages are availabe for public view
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Abstract
Various indices are used to measure platelet functions, for example,the platelet count (PC), mean platelet volume (MPV), the PC to MPV ratio,and platelet distribution width (PDW); PDW measures platelet size distribution.In PE patients, the coagulation-fibrinolytic system is thought to be one of the most seriously affected systems by maternal inflammatory reactions and immune dysfunction. The balance between coagulation and anticoagulation is vital to the regulation of utero-placental circulation and organ perfusion in pregnant woman. An appropriate increase in blood coagulation is important for normal pregnant woman to reduce postpartum hemorrhage and to limit other complications. When this balance is upset in PE patients, the pathogenesis of preeclampsia occurs in the form of spasm of the blood vessels and in turn the bloodstream of the placenta and many organs is blocked by microthrombosis.The super-hypercoagulable state of women with PE may also lead to systematic disorders of metabolism as well as multiple organ dysfunction and may even threaten maternal and fetal lives.To date, there is no effective treatment for PE in addition to the termination of pregnancy. Therefore, a reliable predictor for PE would play an important role in early prevention and intervention.The aim of this work is to investigate the diagnostic value of platelet count (PC), mean platelet volume (MPV), the PC to MPV ratio and platelet distribution width (PDW) for prediction of pre-eclampsia (preceding development of pre-eclampsia).