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Abstract Chronic renal failure is associated with significantly increased morbidity and mortality. It affects almost every system of the body and results in various functional and structural abnormalities. Cardiovascular disease is one of the leading causes of mortality in chronic renal failure patients. In hemodialysis patients, arteriovenous fistula causes a left-to-right shunt leading to chronic volume overload and increasing the risk of pulmonary hypertension. Most of the available studies focused on left ventricular function in dialysis patients, but the impact of dialysis on the development of right ventricular dysfunction has not fully been investigated. The aim of the present study was to assess the right ventricular function in hemodialysis patients using echocardiography (2D, TDI and speckle tracking) modalities. The present study was conducted in Cardiology department, Faculty of Medicine, Menoufia University Hospital during the period from October 2018 to October 2019 on 70 subjects grouped as follows: group I: 50 patients on hemodialysis. group II: 20 healthy subjects, age and sex matched as control group. In the present study, all participants were subjected to complete history taking, full clinical examination, ECG and assessment of cardiac functions using conventional, tissue Doppler and speckle tracking echocardiography. 2D echocardiography was used to assess all cardiac valves to exclude the presence of any organic affection, and to assess wall motion abnormalities, detect rheumatic and congenital heart diseases, assess RVSP, SPAP and FAC. M-mode echocardiography was used to assess aortic & left atrial diameters, interventricular septum thickness during diastole & systole, posterior wall thickness in diastole & systole, left ventricular end-diastolic diameter, left ventricular end-systolic diameter, fractional shortening, LV ejection fraction, and tricuspid annular plane systolic excursion. Tissue Doppler imaging was used to assess annular peak systolic velocity, early and late peak annular diastolic velocities. Speckle tracking echocardiography was used to assess RV peak systolic longitudinal strain and strain rate, RV peak early diastolic longitudinal strain rate, and RV peak late diastolic longitudinal strain rate. In the present study there was no statistically significant difference between the two groups regarding age and sex. |