Search In this Thesis
   Search In this Thesis  
العنوان
Prognostic factors for successful microdissection Testicular Sperm Extraction (Micro-TESE /
المؤلف
Mashaly, Mohamed Hamdy Attia.
هيئة الاعداد
باحث / محمد حمدى عطيه مشالى
مشرف / محمد ابو العينين غلوش
مشرف / ماجد مصطفى رجب
مشرف / طارق احمد جميل
الموضوع
Urology.
تاريخ النشر
2020.
عدد الصفحات
90 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة المسالك البولية
تاريخ الإجازة
13/9/2020
مكان الإجازة
جامعة طنطا - كلية الطب - Urology
الفهرس
Only 14 pages are availabe for public view

from 125

from 125

Abstract

NOA is a condition characterized by absence of sperm in the ejaculate
due to impaired spermatogenesis. NOA is reported in about 60 % of
azoospermic patients and 10 % of all infertile men.
These infertile men require some form of sperm retrieval procedure in
conjunction with intra-cytoplasmic sperm injection to get their offspring.
Micro-TESE is one of the best sperm retrieval procedures for men with
NOA.
Azoospermia may result from pre-testicular, testicular causes affecting
spermatogenesis or post-testicular causes. Pre-testicular causes are including
defect in the hypothalamus or pituitary gland resulting in impairment the
production of FSH and/or LH resulting in secondary spermatogenic failure.
Primary spermatogenic failure is defined as any spermatogenic alteration by
cases other than hypothalamic-pituitary diseases. The severe forms of
primary spermatogenic failure present clinically by azoospermia with
different causes. Testicular causes of azoospermia are collectively referred to
as non-obstructive azoospermia.
Diagnosis of NOA depends on History taking, clinical evaluation,
laboratory investigations such as hormonal profile and testicular biopsy
Recently, there are many achievements in the area of male infertility.
One of them was the introduction of intracytoplasmic sperm injection (ICSI)
for the treatment of male factor infertility due to severely abnormal semen
quality. Another achievement was the extension of ICSI to azoospermic males and the demonstration that spermatozoa retrieved from either the
epididymis or the testis were capable of normal fertilization and pregnancy.
Micro-TESE is one of the most popular sperm retrieval procedures for
men with NOA.
In present study we tried to find out Prognostic factors for successful
Micro-TESE.
In this study 52 men aged more than 23 years old with infertility for
more than 1 year and clinically evident non-obstructive azoospermia with
two semen analysis show azoospermia.
All Patients underwent Micro-TESE and according to Micro-TESE
result, they were divided into 2 groups Negative SRR group and Positive
SRR group.
The success rate of Micro-TESE in or study was 46.15%. As there
were 28 patients with positive SRR and 24 patients with negative SRR.
We compared between the two groups according to preoperative
factors included age, FSH, LH, estradiol, testosterone, prolactin and
testicular volume and intraoperative factors included seminiferous tubular
diameter and opacity.