الفهرس 
Speckle Tracking EchocardiographyOnly 14 pages are availabe for public view
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Abstract
CAE is defined as localized or diffuse dilatation of coronary artery
lumen exceeding the largest diameter of an adjacent normal vessel more
than 1.5 fold Isolated CAE, without coronary stenosis and other heart
diseases is rare. Underlying etiological causes of CAE include
atherosclerosis, congenital origins, inflammatory and connective tissue
diseases. CAE may result in slowed blood flow, coronary vasospasm,
dissection and thrombus formation leading to increased risk of cardiac
morbidity and mortality
2D-STE is a novel technique enabling more reliable and
comprehensive assessment of myocardial function by obtaining the
myocardial strain and strain rate in longitudinal, radial and
circumferential directions .longitudinal functions deteriorate earlier than
radial and circumferential functions in myocardial dysfunction
Objective:
The aim of this work is was to evaluate longitudinal left ventricular
mechanical function in patients with coronary artery ectasia using 2D
speckle tracking echocardiography
Methodology:
The study conducted on 60 patients who had invasive coronary
angiography. Patients had been divided into 2 groups. The First group (A)
included 40 patients with isolated coronary artery ectasia. The second
group (B) was a control group which included 20 patients with
angiographically normal coronaries.
Results:
Regarding Demographic data of the patients:
No significant differences between group A and B regarding age, gender,
HTN and smoking.
Regarding Conventional 2D Echocardiography:
No significant differences between the study group and control group
regarding conventional TTE findings.
Regarding Mitral Annular TDI Echocardiography:
è wave velocities were significantly lower in group A and E/è were
significantly higher in group A. So, diastolic dysfunction is significantly
higher in group A than B.
Regarding 2D-STE:
There is significant reduction in global longitudinal strain in group A
than B while no significant differences between the two groups regarding
radial and circumferential strain. There is a relation between the ectatic
vessel and the regional longitudinal strain of the corresponding segments.
Correlation Analysis:
Patients with CAE has LV systolic dysfunction, when evaluated with
2D-STE, in the form of reduction of the global longitudinal strain. Also,
there is a relation between the ectatic vessel and the regional longitudinal strain of the corresponding segments.