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العنوان
Acute Pulmonary Embolism At Tanta University Hospital: Single Centre Registry /
المؤلف
Elkhateeb, Alaa Raafat Elesawi.
هيئة الاعداد
باحث / علاء رافت العيسوى الخطيب
مشرف / سهام فهمى بدر
مشرف / تيمور مصطفى عبد الله
مشرف / احمد فاروق الاعرج
الموضوع
Cardiovascular.
تاريخ النشر
2020.
عدد الصفحات
105 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
26/8/2020
مكان الإجازة
جامعة طنطا - كلية الطب - Cardiology
الفهرس
Only 14 pages are availabe for public view

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from 131

Abstract

Pulmonary embolism (PE) is a major cause of morbidity and mortality worldwide, and has significant negative impacts on quality of life, healthcare costs, and longevity. Registries have been created to record ‘real-life’ clinical features and management of patients with PE. We aimed to describe a comprehensive view of the clinical presentation, demographic data, treatment modalities and short-term outcome at hospital discharge and 3 months after discharge for patients presented with acute pulmonary embolism at Tanta university hospital to improve the level of care of those patients. This study was conducted on 150 patients with confirmed acute PE presented to Tanta university hospitals. The study duration was 1 year from April 2019 to May 2020 We focused on a group of common risk factors for PE and determined prevelance of each in our enrolled patients, we found increase some risk factors obesity and bed rest > 3 days were the most prevalent risk factors followed by active cancer, estrogen use and lower limb fracture. We found that symptoms in this study are near to other registries and ESC guidelines 2019 with the commonest symptom was dyspnea and chest pain and the least symptom was hemoptysis.We found certain ECG signs more prevalent in our patients and these signs related to RV strain with sinus tachycardia the commonest sign followed by S1Q3T3 sign and the least was right axis deviation. Most of patients had sPESI 1 or more and the majority of patients classified as intermediate low risk patients. Our enrolled patients received in-hospital and long term treatment according to ESC guidelines recommendations with increase in the use of UFH, O2 mask as oxygen support and the majority of patients received warfarin as long term anticoagulation, but there were lack of certain treatment measures as percutaneous catheter-directed treatment and surgical embolectomy. We found that presence of active cancer and patients with high risk stratification were independent predictors of mortality. Other factors assosciated with increased mortality were impaired RV systolic function, high PESI score, presence of RBBB in ECG, and presence of congestive heart failure. We found increased risk of bleeding in male patients with intermediate high or high risk category especially those received UFH and fibrinolytic therapy. We also found that autoimmune disease and previous history of VTE were independent predictors of VTE recurrence.