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Abstract Diaphragmatic dysfunction has become a subject of major concern in critical ill patients, because it is associated with a higher rate of weaning failure, increased duration of mechanical ventilation and consequently increased the length of stay in ICU (Kim WY et al, 2011). Ultrasound evaluation of the diaphragm is simple, non-invasive, and readily available at the bedside and increasingly used both in the clinical and research settings (Zambon M et al., 2017). It can assess the diaphragm dysfunction and its influence on weaning outcome in mechanically ventilated patients (Ali ER and Mohamed AM et al, 2016). Aim of the Work: Sonographic assessment of diaphragmatic function as a predictor for weaning from mechanical ventilation. Patients and methods: This study included 30 patients admitted in ICU units of Fayoum university hospital who are invasively mechanically ventilated during the period from July 2018 to July 2019. All patients were subjected to full medical history taking, detailed general and local clinical examination ,chest X ray, laboratory assessment, using ultrasound machine to measure diaphragmatic excursion (DE), diaphragmatic thickening fraction (DTF), contraction velocity, and relaxation rate during first 24 hours of intubation, first 24 hours of weaning process and among successful weaning group the same measures are assessed after extubation (within first 48h) and before discharge or referral to ward. |