الفهرس 
Thyroid gland anatomyOnly 14 pages are availabe for public view
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Abstract
Thyroid gland elastography is a reliable, non-invasive and practical method for routine assessment of thyroid nodules to select cases for FNAC, decrease the number of unnecessary biopsies, and consequently decrease the hazards and costs. It can be an effective method in changing the clinical decisions regarding indeterminate thyroid nodules, as cases with an elasticity score of 4 and 5 are considered to be highly malignant. Diffusion weighted MRI is a non-invasive, non-radiative & accurate method in the assessment of the thyroid nodules providing a good determining tool by the measurement of the ADC value. The benign nodules had higher ADC values than the malignant ones. The aim of this study was to assess the role of ultrasound elastography and diffusion-weighted MRI in differentiation of benign and malignant thyroid nodules. The present study 28 patients with thyroid nodules (10 males & 18 females), age ranging between (17 and 65 years) underwent thyroid ultrasound examination. Patients were categorized according to ACR-TIRADS then real-time sonographic elastography was done, elastography score were classified on a scale of 1–5 according to 5-points Rago et al criteria, then average strain ratio of the nodule was measured. Receiver operating characteristic (ROC) curve analysis was used to determine the optimal cutoff strain ratio for differentiating benign and malignant thyroid nodules.MR examination was performed for all patients using the same scanning parameters. Diffusion weighted images was performed, then ADC maps were reconstructed. Average ADC value of the nodule was measured. Receiver operating characteristic (ROC) curve analysis was used to determine the optimal cutoff ADC value for differentiating benign and malignant thyroid nodules. Fine needle aspiration biopsy performed under US guidance for all 28 cases; it was diagnostic in 24 cases, while 4 cases needed surgical histopathology for final diagnosis. 18 nodules were benign (64.3 %) & 10 were malignant (35.7 %).