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العنوان
Effect of Sofosbuvir (sovaldi) on Submandibular Salivary Gland in Adult Male Albino Rats :
المؤلف
Abdeen, Asmaa Mahmoud.
هيئة الاعداد
باحث / أسماء محمود عابدين
مشرف / طارق أحمد عيسوي
مشرف / سحر سيد محمد
الموضوع
Teeth - Diseases - Diagnosis. Histology, Pathological.
تاريخ النشر
2020.
عدد الصفحات
180 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
طب الأسنان
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة المنيا - كلية طب الأسنان - بيولوجيا الفم
الفهرس
Only 14 pages are availabe for public view

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Abstract

The aim of the present study was to evaluate the effect of oral administration of sofosbuvir (SOF) in different durations on the structural and ultra-structural features of the submandibular salivary glands of adult male albino rats.
Immunohistochemical (PCNA) results:
Statistical analysis of PCNA immunoreactivity revealed predominantly negative area masked by the blue binary color in the control group.
Statistical analysis of PCNA immunoreactivity revealed significant decrease in the area masked by the blue binary color from subgroup (1) to subgroup (3) in the experimental subgroups.
Statistical analysis of PCNA immunoreactivity revealed significant increase in the area masked by the blue binary color in the recovery group.