الفهرس 
contentOnly 14 pages are availabe for public view
 |  | from | 81 |  |  |
| | | from | 81 | | |
Abstract
HF has high mortality with 5 year survival rate below 50%. CRT is an effective treatment as it improves symptoms, exercise capacity, and systolic function. It also reduces hospital readmissions and, decreases mortality, but 20–30% of patients do not respond to CRT. Different studies tried to determine predictors of response. We investigated the predictors of response to CRT using CMR assessment of scar burden and its relation to site of LV lead implantation. We found that the underlying etiology of heart failure was not related to the response to CRT, responders showed significant improvement in NYHA class, significant reverse LV remodeling in form of responders had significant higher ejection fraction and lower end systolic volume after implantation than non-responder, result in significant decrease of mitral regurge severity. Scar burden in CMR scan was significantly higher in non-responders, and responders had significantly low percentage of fibrosis at segment related to LV lead implantation.