الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Diuresis renography is the most commonly test used tool to investigate the urinary tract dilatation, which differentiate between obstructed and non-obstructed systems and evaluate the glomerular filtration rate (GFR). This test is widely accepted because of its convenience and noninvasiveness. Prompt clearance of the radiopharmaceutical from the renal pelvis with a T1/2 of less than 10 min is a normal response, values between 10 and 20 min are considered equivocal results, and a T ½ greater than 20 min suggests obstruction. Objective: This study aims to assess the optimal timing of furosemide injection in diuretic renography in order to obtain the most accurate diagnosis.
Materials and methods: This study included 300 renal units (RU) were examined at Urology and Nephrology Center- Mansoura University from 2016 to 2019 by F+10 min diuretic renography protocol. Results: One hundred and seventeen (RU) of 300 (RU) gave no response to diuresis and were diagnosed as obstructive kidneys. One hundred and twenty one (RU) revealed the excretion of kidneys were delayed but improved diuresis response and were diagnosed as non-obstructive kidneys, The remaining sixty two (RU) showed equivocal response to diuresis after diuretic were done and underwent F-15 min protocol of diuretic renography. Twenty (RU) were proved to be non-obstructed, forty two (RU) showed complete obstruction. Comparing the results of F+10min protocol with F-15 min protocol for the 62 (RU) with equivocal response 42 (RU) revealed as an obstructive kidneys by using F-15min protocol with mean ± SD T½ values 36.64min±14.70min which was 15.19min±2.70 by F+10min (p=.000). The other twenty (RU) revealed as non-obstructive kidneys and have mean ± SD T½ values 9.83min±3.33min by using F-15 min protocol which was 14.43±2.96min by using F+10 min (p=.0.000). A p value < .05 was considered significant. Conclusion: F-15 min diuretic renography protocol can be considered as the most sensitive and gold standard method for making a distinction between urinary obstruction and non-obstruction.