الفهرس 
Review of literatureOnly 14 pages are availabe for public view
 |  | from | 112 |  |  |
| | | from | 112 | | |
Abstract
Epilepsy is one of the most common neurological disorders worldwide. Epilepsy is diagnosed after a patient has two or more unprovoked seizures.
Epilepsy is a potentially life-threatening condition and is associated with increased mortality particularly in patients with chronic epilepsy. Possible causes of death include a complication of epilepsy, e.g. trauma, aspiration of gastric content, convulsive status epilepticus, a complication of drug treatment or a related underlying cause.
Epilepsy affects markedly child behavior and cognition, Behavioral difficulties that are most commonly seen in epilepsy consist of depression, anxiety, agitation and irritability, aggression, hyperactivity, decreased attention span or inattention, autistic disorder.
The Cognitive comorbidities in epilepsy are often attributed to seizures and antiseizure medications, referred to as antiepileptic drugs (AEDs). However, it is important to understand that cognitive comorbidities in epilepsy are often related to the underlying aetiology, age of onset of epilepsy, frequency and location of seizures, and, potentially, epileptiform abnormalities, as well as AEDs.
The present study was designed to evaluate cognition and behavior among epileptic children to study the relation between epilepsy and cognition and behavior and to detect if epilepsy affects cognition and behavior.
This study was carried out in pediatric Neurology outpatient Clinic and Neurology Unit, Menoufia University Hospitals on (60) children with the diagnosis of epilepsy and (20) clinically healthy non-epileptic children were taken as a control group. The sixty epileptic patients were classified into three groups, the first group (20 children) were recently diagnosed children with epilepsy who didn‘t receive antiepileptic drugs or on drugs for ≤ month only, the second group (20 children) were controlled on antiepileptic drugs for ≥ one year, the third group (20 refractory epileptic children).
All the studied groups were subjected to detailed history taking with special emphasis on history of present illness including Onset, course, duration of epilepsy, type of seizures (GTCs,absence,focal), duration of treatment, and type of antiepileptic dug used, duration of attack, controlled on treatment or not, Perinatal history, Developmental history (mental, motor and social) and Family history concerning similar condition in family and consanguinity. Neurological examination (cranial nerves examinations, gait, muscle tone, muscle power, reflexes and sensory system affection with stress on mental status. Neurocognitive assessment by Wechsler test, assessment of behavior by asking their parents to answer questions of revised behavior problem checklist.
In our study there was no significant difference between patients‘ groups as regarding demographic data such as age, sex, residence, family history of convulsions and parents’ consanguinity, motor, mental and social development.
There was no significant difference between patient groups regarding perinatal history except regarding gestational age, NICU admission and jaundice. We found that controlled group 20% admitted to NICU. we noted that 15% of refractory group was preterm and no history of preterm in newly diagnosed and controlled group.