الفهرس 
Review of LiteratureOnly 14 pages are availabe for public view
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Abstract
Acute Ischemic stroke Is a major health problem it is one of major causes of mortality and disability in Adults, Mechanical thrombectomy nowadays is the only therapy approved for large vessels occlusion stroke which account about 20% of cases of ischemic stroke and presents usually with severe neurological deficit.
Accurate and prompt prediction of Recanalization, functional outcome, and post procedure heamorrhagic transformation in patients with ischemic stroke treated with mechanical thrombectomy is essential for clinicians, patients and families.
So that this study was carried out to search for any clinical characteristics (Age, Sex& Risk Factors) or imaging markers (NCCT ASPECTS, CBS, CS, Clot Site& Clot Permeability) that could be used to predict recanalisation,clinical outcomes and post procedure heamorrhage in ischemic stroke patients undergoing mechanical thrombectomy.
This study was conducted on thirty four patients of both sexes They were 15 females (44.1%) and 19 males (55.9%) with Ischemic Cerebrovascular stroke admitted to the neurology department of Alexandria university hospitals from January 2017 to December 2017 treated with mechanical thrombectomy and follow up done three months after the acute stroke. it was approved by the ethics committee of the Menoufia University Hospital. The age of the patients included in this study was ranged from 25 – 81 years old.
The included patents were subjected to full history taking, general examination, complete neurological examination, laboratory work up (routine laboratory investigations for aetiology of CVS ).
The clinical severity of stroke was assessed with national institute of health stroke scale at admission and patients were divided into minor, moderate, moderate to severe and severe.
They were also subjected to radiological imaging using NCCT brain (to exclude cerebral heamorrhage, and ASPECTS scoe), CTA (to Asses CBS, CS. Clot site and Residual flow through Thrombus) and CTP to search for mismatch in patients presented with walk up stroke and presented mpre than six hours from onset.
All patients were treated with mechanical thrombectomy and recanalization rate was assessed with mTICI score and divided into good (TICI 2b-3) and Bad (TICI 0-2a) using DSA after the procedure.
The clinical outcome of stroke was assessed 3 months later using modified Rankin scale. Favourable outcome was defined as MRS (0-2) while unfavourable outcome was defined as MRS (3-6).
This study showed that:
1- Regarding clinical outcome there were statistically significant difference between outcome and pretreatment NIHSS, pretreatment ASPECTS score, Clot burden score, Collateral score and there were no statistically significant difference Between Outcome and clot site or Residual flow.
2- Regarding post procedure heamorrhage there were statistically significant difference between post procedure heamorrhage and pretreatment ASPECTS score, there were no statistically significant difference between post procedure heamorrhage and clot site, Residual flow, Clot burden score or Collateral score.
3- Regarding recanaliztion there were no statistically significant difference between it and any of the studied variables.