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العنوان
effect of glycated hemoglobin a1c-based adjusted glycemic variables on the outcome of diabetic patients presenting with acute coronary syndrome/
المؤلف
Khalil, Maged Osama Aziz Guirguis.
هيئة الاعداد
باحث / ماجد أسامة عزيز جرجس خليل
مشرف / يحيي مصطفى غانم
مشرف / محمد عبد الرؤوف قرنى
مشرف / باسم نشأت بشاى
الموضوع
Emergency Medicine.
تاريخ النشر
2020.
عدد الصفحات
P59. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
9/12/2020
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Emergency Medicine
الفهرس
Only 14 pages are availabe for public view

from 70

from 70

Abstract

Acute hyperglycemia is a frequent finding in patients presenting to the emergency department (ED) with acute coronary syndrome (ACS) in both diabetic and non-diabetic patients.
Unlike non-diabetic patients, diabetics with acute cardiac event like ACS with high admission blood glucose level are likely to have more than a factor that raise the measured glycemic value. Hyperglycemia alone may be rendered to a response to acute physiological stress, due to chronic hyperglycemic state that represents poor glycemic control or because of both.
So it is necessary to consider chronic hyperglycemia in diabetic patients when studying the association between blood glucose level and adverse outcomes in patients with ACS or when hyperglycemia in this group of patients is going to be used as a biomarker for predicting the outcome.
We used the glycemic gap instead of the absolute admission blood glucose value targets elimination of the effect of chronic hyperglycemia on the measured admission blood glucose to identify the major contributor in that presenting hyperglycemia.
Our major target of this study was to find the correlation between the glycemic gap and the clinical outcome in diabetic patients with ACS. In addition, we sought to justify the use of the glycemic gap as a biomarker which affects diabetic patients presenting to the ED with ACS.
We prospectively followed 100 successive diabetic patients who were presented to the ED of Alexandria Main University Hospital (AMUH) and admitted to hospital with ACS. All of the enrolled patients were evaluated with full history, complete examination, ECG and admission blood glucose measurement.
Those patients were observed during their hospital stay, searched for the occurrence of Major Adverse Cardiac Events (MACE). Their hospital stay length with days was also recorded. The glycemic gap