الفهرس 
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Abstract
Depression is defined as a condition affecting negatively the feelings, thinking and the way of acting; manifested by loss of interest, feelings of sadness, decrease in activities once enjoyed before, discouragement or hopelessness. Major depression disorder itself being a big burden worldwide and affecting general population at rate of 17% regardless of age consideration. Diagnosed and treated, MDD is a curable psychiatric condition.
Suicide is defined as act of intentionally causing own death. It is the 10th cause of death in USA with 44,000 deaths every year and in 2015 about 800,000 suicide deaths reported worldwide. MDD leads to suicide of about 80% in all suicide attempts committed by psychiatric patients.
The aim of the present case control study was to assess the risk factors of suicide in sample of MDD patients in comparison with non-suicide major depressive disorder subjects through a case control study done in Alexandria University hospitals.
For every participant of current study a, data collection done by completing questionnaire divided in three parts: a translated demographical data, Arabic validated version of Hamilton depressing rating scare and validated Arabic version of Columbia–suicide severity rating scale (CSSRS).then followed by sampling blood for analysis to consider random TSH and morning serum cortisol.
The collected data were analyzed using Chi-square test (X2), Monte carlo test (MCp), Fisher Exact test (FEp), Mann Whitney test (Z).
The overall results of this study showed that:
• Considering gender there are 7 male and 13 participants for each group of current study.
• The mean (± SD) ages were 27.95±9.17 years for group I subjects and 33.50±11.63 years for group II respectively.
• Marital status in group I versus group II; single 9(45%) versus 6 (30%) group II; married 11 (55%) versus 11 (55%); divorced/separated 0 versus 3 (15%) participants. This factor was not associated with statistical difference (P=0.245).
• Educational level in group I versus group II; Illiterate 1(5%) versus 0; Elementary/primary 4(20%) versus 5(25%); Secondary school 3(15%) versus 5(25%); Vocational education 3(15%) versus 4(20%); College/University 9(45%) versus 6(30%).
• The daily occupation of participants of group I versus group II were distributed as Student 7(35%) versus 4(20%), Office 1(5%) versus 2(10%), Industry 5(25%) versus 2(10%), Private 1(5%) versus 0.
• Home and family structure of participants in group I versus group II; living alone 0% versus 1(5%); living with parents 10(50%) versus 7(35%); married and live with their families 10(50%) versus 11(55%) and living with non-family members 0% versus 1(5%