الفهرس 
Introduction & Aim of the workOnly 14 pages are availabe for public view
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Abstract
After ethical committee approval and written informed consent were obtained from all patients, this prospective randomized double blind controlled study was carried out at El-Minia University Hospital during the period from April 2019 to December 2019 on 60 adult patients of both sex, their age ranged from 18-70 years of American society of anesthesiologists (ASA) physical status I and II scheduled for elective laparoscopic cholecystectomy under general anesthesia.
This study aimed to evaluate analgesic efficacy of ultrasound guided Quadratus Lumborum block versus Erector Spinae block in laparoscopic cholecystectomy.
The patients were randomly allocated into three parallel equal groups of 20 patients each by using a computer-generated table and the randomization sequence was concealed in sealed envelopes assignment held by an assistance who not involved with the clinical management or data collection.
group Q ”Quadratus Lumborum blo¬ck”:
Received bilateral ultra sound guided Quadratus Lumborum block using 20 ml Bupivacaine0.25 % (on each side), put in mind the safe dose of local anesthetic.
group E ”Erector spinae block”:
Received bilateral ultra sound guided Erector Spinae block using 20 ml Bupivacaine0.25% (on each side), put in mind the safe dose of local anesthetic.
group C ”Control group”:
Didn’t receive any of previous blocks neither Quadratus Lumborum nor Erector Spinae blocks.
All patients were assessed in terms of:
1- Hemodynamic parameters arterial oxygen saturation:
A) Intraoperative:
• HR, MAP and SaO2 were recorded immediately before and after induction of anesthesia, and at 5,10,20,30,40,50,60 min. after the block then every 15 min. until the end of the operation.
• Total intra operative fentanyl requirement.
• Total number of patients needed fentanyl.
B) Postoperative:
• Recovery score
• HR, MAP and SaO2 at 1, 2, 4, 6, 8, 12, 16, 20, 24 hour post-operative.
• VAS at 1, 2, 4, 6, 8, 12, 16, 20, 24 hour post-operative.
• Time to first analgesic request.
• Total analgesic requirement of fentanyl.
• Incidence of any side effect.
• Time of discharge from recovery room.
Our results recorded that the patient characteristics (age, gender, weight, ASA classification, surgical time and operation type) and SaO2 were comparable between three studied groups.
Conclusion
The use of both interfacial plane block either ESB or QLB were safe and effective in intraoperative and postoperative analgesia decrease VAS score, but the ESB characterized by delayed 1st analgesic request time with decreased total analgesia within 24hr., more decrease in VAS score and longer analgesic duration than QLB which last for 16hr. while QL group the duration of analgesia was 12hr.