الفهرس 
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Abstract
This work was conducted to study the of chemical composition and some active compounds such as total phenols, total flavonoids and identification of phenolic compounds using HPLC of date palm pith called (paltimo or heart of palm) (Phoenix dactylifera) powder (DPP) . Study the effect of as powder on biological, biochemical, anti-obesity and hepatoprotective changes in male albino rats was considered. The efficiency of different concentrations (5 and 7%) of date of palm pith as powder on obese hepatointoxicated changes in male albino rats was in the scope of this investigation. Also, some physiological characteristics such as (liver functions, kidney functions, lipid profile, glucose levels, SOD, CAT, GPX and internal organs weight) in tested albino rats were also measured. Histological investigation was carried out on liver and kidney. A total of 60 adult normal male albino rats Sprague Dawley strain weighing 140±10 g were obtained from Vaccine and Immunity Organization, Ministry of Health, Helwan Farm, Cairo, Egypt. Rats were injected subcutaneously at a dose of 0.2 ml/100 g body weight of 40 ml/l CCl4 dissolved in paraffin oil. Carbon tetrachloride was injected three times per week for 4 consecutive weeks. Liver intoxication was determined at the end of experimental part by sacrificing rats and histopathological examination. Obesity was induces in normal healthy male albino rats by feeding on high fat diet (HFD) 20% animal lipid (cheap fat) supplemented in the basal diet and used as a positive control group. After this adaptation period, rats divided into 4 groups, each group consisted of 6 rats as follows:
SUMMARY
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group (1): Rats will feed on basal diet as a control negative group. group (2): Rats inflicted with hepatotoxicity, obesity and obesity / hepatotoxicity and fed on the basil diet and used as a positive control groups (control+). group (3): Rats inflicted with each of 3 ailments and fed on the basal diet with 5 % DPP. group (4): Rats inflicted with each of 3 ailments and fed on 7% date palm pith powder. During the experimental period, the body weight and feed intake were estimated weekly and the general behavior of rats was observed. The experiment lasted for 42 days, at the end of the experimental period each rat was weighted separately then, rats were slaughtered and collect blood samples. Blood samples were centrifuged at (4000 rpm) for ten minute to separate blood serum, then were kept in deep freezer till using.