الفهرس 
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Abstract
This study was conducted as a case-control study to determine the patterns of ACE gene polymorphism and serum ACE levels in psoriatic patients and healthy controls in Ismailia. It was carried out at Dermatology, Venerology and Andrology Department in Suez Canal University Hospital. The studied populations included two groups: study group (psoriatic group) included 20 patients with psoriasis and control group included 20 healthy adults who were age and gender matched to the study group.
The mean age of psoriasis group was matching the control group without statistically significant difference (37.3±14.7 years and 39.1±7.6 years, respectively) (p>0.05). Also, psoriasis and control groups were matched for gender without significant difference (female/male= 45.0%/55.0% and 55.0%/45.0%, respectively; p>0.05). Figures (1-2) show the mean age and gender distribution in both studied groups.
About 50.0% of the psoriatic patients had mild disease according to PASI, 10.0% had moderate disease, and 40.0% had severe disease.
ID genotypes were significantly higher among the psoriatic group in comparison to the control group (40.0% versus 15.0%, respectively), while II genotypes were significantly higher among the control group in comparison to the psoriatic group (85.0% versus 55.0%, respectively) (p<0.05).