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العنوان
STUDY THE EFFECT OF SWEET POTATO (ROOTS AND LEAVES) ON BIOLOGICAL, BIOCHEMICAL AND HISTOLOGICAL CHANGES ON DIABETIC RATS /
المؤلف
Abo El-Nasr, Abeer Fathy.
هيئة الاعداد
باحث / عبير فتحي أبو النصر
مشرف / عماد محمد عبد الحليم الخولي
مناقش / أشرف فهمي عبد الحليم شروبه
مناقش / سهام عزيز خضر
الموضوع
nutrition.
تاريخ النشر
2021.
عدد الصفحات
138 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
اقتصاد منزلي
تاريخ الإجازة
9/3/2021
مكان الإجازة
جامعة المنوفية - كلية الإقتصاد المنزلى - التغذية وعلوم الأطعمة
الفهرس
Only 14 pages are availabe for public view

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Abstract

This study was conducted to study the effect of sweet potato root and leaves as powder on biological, biochemical and anti-diabetic changes of male albino rats. Study the efficiency of different concentrations (2.5 and 5 %) of sweet potato root and leaves as powder and anti-diabetic changes of male albino rats. Also, some physiological characteristics such as BWG, FI, FER and internal organs weight were determined. Some biochemical parameters (glucose levels, liver functions, kidney functions, TC, TG, HDL-c, LDL-c, VLDL-c and) and hematological parameters (RBC, WBC, hemoglobin and platelet) in tested albino rats were also measured. Active compounds in sweet potato root and leaves such as phenolic compounds and phytochemicals of using HPLC will also determine.
The use of (48) male albino rats weight ranges between (140-150 g ±10g) during the experiment period. Rats will feed on basal diet prepared according to (AIN, 1993) for seven consecutive days to make adjustment and rats are divided into 8 groups each group that consists of six rats as follows:
group (1: Rats were feed on basal diet as a control negative.
group (2): Rats were injected with alloxan 150 mg and used as positive control group.
group (3): group infected diabetes and was feed on sweet potato leaves powder at does 2.5% of the weight of the diet.
group (4(: group infected diabetes was feed on sweet potato leaves powder at does by 5% of the weight of the diet.
group (5): group infected diabetes was feed on sweet potato roots power by 2.5% of the weight of the diet.
group (6): group infected diabetes was feed on by sweet potato roots power 5% of the weight of the diet.
group (7): group infected diabetes was feed on mixture 1:1 of sweet potato leaves and roots by 2.5% of the weight of the diet.
group (8): group infected diabetes was feed on mixture 1:1 of sweet potato leaves and roots 5% of the weight of the diet.
During the experimental period, the body weight and feed intake were estimated weekly and the general behavior of rats was observed.
The experiment will take 28 days, at the end of the experimental period each rat weight separately then, rats are slaughtered and collect blood samples.
The obtained results could be summarized in the following:
6.1. Chemical composition of sweet potato roots:
1. The moisture, protein, fat, ash, fiber and energy value of sweet potato roots as wet weight were 67.34%, 2.83%, 0.40%, 2.29%, 2.54%, 24.60% and 113.32 kcal/100g, respectively.
2. The moisture, protein, fat, ash and energy value of sweet potato roots as dry weight were 9.35%, 8.67%, 1.22%, 7.01%, 7.78%, 75.32% and 331.70 kcal/100g, respectively.
6.2. Chemical composition of sweet potato roots:
1. The moisture, protein, fat, ash and energy value of sweet potato roots as wet weight were 83.70%, 4.67%, 0.41%, 1.68%, 1.92%, 7.62% and 113.32 kcal/100g, respectively.
2. The moisture, protein, fat, ash and energy value of sweet potato roots as dry weight were 8.72%, 28.60%, 2.52%, 10.90%, 114.18%, 6.80% and 331.70 kcal/100g, respectively.
6.3. Phytochemicals characteristics of sweet potato roots and leaves:
1. The sweet potato roots have higher total phenols, total flavonoids and scavenging activity contents. The mean values were 164.17 mg GAE / 100 g DW, 130.15 mg CAT/100g DW and 46.50 %, respectively.
2. While sweet potato leaves were recorded lower total phenols, total flavonoids and scavenging activity contents. The mean values were 80.75 mg GAE / 100 g DW, 40.32 mg CAT/100g DW and 41.40 %, respectively.
6.4. Phenolic compounds of sweet potato leaves fractionation by HPLC analysis: