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العنوان
Impact of phacoemulsification cataract extraction on corneal endothelium and anterior chamber biometric changes in eyes with narrow angle glaucoma /
المؤلف
Khattab, Khaled Mohamed Helmy.
هيئة الاعداد
باحث / خالد محمد حلمي خطاب
مشرف / هشام ابراهيم السروجي
مشرف / شريف السعيد الخولي
مناقش / انيا كامل فرج
الموضوع
Angle Closure Glaucoma.
تاريخ النشر
2021.
عدد الصفحات
61 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب العيون
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم طب و جراحة العيون
الفهرس
Only 14 pages are availabe for public view

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from 73

Abstract

Primary angle closure glaucoma is a major cause of blindness worldwide. It is a disease of ocular anatomy that is related to pupillary block and angle crowding mechanisms of the filtration angle. Eyes with decreased axial length, anterior chamber depth and filtration angle width are at higher risk for primary angle closure. Cataract and glaucoma are often found to coexist since both affect elderly. Treatment of eyes with Primary angle closure glaucoma and cataract includes glaucoma surgery alone followed by phacoemulsification or glaucoma surgery combined with cataract surgery. However, it was reported that cataract extraction with posterior chamber IOL implantation as a single procedure has a clinically significant role in the control of co-morbid glaucoma as it can make the anterior chamber wider and deeper. Phacoemulsification surgery is performed in a limited confined space exposing the endothelial cells to mechanical and thermal damage during the procedure. The results of this study showed that: • Phacoemulsification with posterior IOL implantation was performed to all studied patients and the anterior chamber biometric parameters were recorded pre and post-operative using the rotating Scheimpflug camera imaging of Pentacam showing significant increase in anterior chamber angle, depth and volume. • Quantitative and qualitative Assessment of post-operative endothelial cell loss was done non-invasively by the specular microscopy showing relative endothelial cell loss proportional to cataract density. • Phacoemulsification as a single procedure in a patient with primary angle closure glaucoma and coexisting cataract beside its visual benefits, it deepens the anterior chamber, widens its angle and increases its volume. The lesser density of cataract, the lesser destructive effect on corneal endothelial cells by the phaco ultrasound power conducted in a shallow anterior chamber. So early phacoemulsification is thought to be effective in controlling the anatomical risk factors of narrow angles and more limiting for iatrogenic endothelial cell loss.