الفهرس 
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Abstract
This thesis is subdivided into the following chapters:
1. Introduction:
This part incudes literature survey on the chemistry, various synthetic
routes for heterocycle containing molecules is extensively studied for
their synthesis and their applications not only in medicinal chemistry, but
also in optics, electronics and material sciences.
2. Theoretical discussion:
This chapter includes the theoretical concepts of the methods adopted for
the synthesis of the designed compounds with reference to the knowledge
available in literature and structural elucidation by various spectroscopic
means.The sequences of reactions followed in the preparation of the
target compounds are summarized in the following schemes.
Synthesis of Schiff base (3) as key intermediate [1]was prepared in
excellent yield condensing by equimolar amounts of 2-cyanoaceto
hydrazide with o-bromobenzaldehyde in 50 ml absolute ethanol with 2-3
drops of glacial acetic acid as catalyst (Scheme 1).The starting compound
1,6-Diamino-4-(2-bromophenyl)-2-oxo-1,2-dihydropyridine-3,5-
dicarbonitrile (5) was prepared by two pathways (Scheme 1). The first
pathway consists of refluxing an alcoholic solution of 2-(2-
bromobenzylidene) malononitrile (2) with 2-cyanoacetohydrazide or N’-
(2-bromobenzylidene)-2-cyanoacetohydrazide (3) with malononitrile in
presence of piperidine as catalyst (Scheme1). 4-(2-bromophenyl)-2-oxo-
1,2,3,4-tetrahydropyridine-3,5-dicarbonitrile (4) was isolated (Scheme 1)
from dehydration of product (5) in presence of trifluoro acetic acid as
solvent.