الفهرس 
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Abstract
Almost all dermatology canine patients have a primary or underlying disease that causes secondary affections. These affections must be eliminated and prevented but will recur rapidly unless the primary disease is identified and controlled. In this study, primary dermatological diseases were investigated as well as concurrent secondary affections to reach a definitive diagnosis that will lead to proper treatment and cure. The present work included 67 dogs which divided into 2 groups. Control group (20 apparently healthy dogs) and diseased group (47 dog). All dogs were clinically examined; blood samples were collected from cephalic vein for estimation of CBC, ALT, AST, GGT , BUN, Creatinine, Thyroid profile FT4, TSH and Cortisol. Only diseased dogs were subjected to skin scraping examination while biopsies from skin lesions as well as healthy adjacent tissue were obtained for histopathological examination. Results showed significant leukocytosis in diseased group compared to control group. Skin scraping revealed mites (Sarcoptes scabiei and demodex canis) infestation. Also, ectothrix and endothrix spores of dermatophytes were detected (Microsporum canis). Histopathological examination revealed various changes in epidermis as well as dermal layer in different dermopathies.
Conclusion: the present work indicated that clinical examination, skin scraping, and laboratory tests (CBC, Biochemistry and hormonal profiles) for different dermopathies in dogs will aid the initial diagnosis whereas histopathological examination for skin biopsy will guide to a definitive diagnosis and furthermore specific therapeutic strategies.