الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Quinoline and its derivatives represent an important class of nitrogen containing heterocycles as they are useful intermediates in organic synthesis and possess a broad spectrum of biological activities, such as anti-asthmatic, anti-inflammatory and anti-malarial activity. Also, quinolines are one of the most studied moieties in cancer chemotherapy field. Hence, synthesis of novel compounds with potent biological activities is important in medicine. Significant research is directed into the development of new quinoline based structures and new methods for their preparations. In the past, synthesis of complex molecules was accomplished by step-wise reaction. This was time consuming and yield was generally low. Nowadays, multi-component reactions are being used since three or more substrates can be reacted in a one-pot reaction. Therefore, yields are higher, and the reaction is more efficient.