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العنوان
IL-37 inhibits the Production of Inflammatory Cytokines in Peripheral Blood Mononuclear Cells of Patients with Systemic Lupus Erythematosus; Correlation with Disease Activity /
المؤلف
Mohamed, Nora Abdel El-moneum.
هيئة الاعداد
باحث / نورا عبد المنعم محمد
مشرف / مر?ت اسماعيل عبدالعظيم
مشرف / إيناس أبوالخيرعبدالعليم
مشرف / رباب عفيفي محمود
الموضوع
Systemic lupus erythematosus. Lupus Erythematosus, Systemic. Monocytes.
تاريخ النشر
2019.
عدد الصفحات
123 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
إعادة التأهيل
الناشر
تاريخ الإجازة
1/11/2019
مكان الإجازة
جامعة بني سويف - كلية الطب - الروماتيزم والتأھيل
الفهرس
Only 14 pages are availabe for public view

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from 129

Abstract

This present study aimed to measure the serum levels of IL-37 in patients with systemic lupus erythematosus (SLE) and to investigate its role in SLE, including its correlation with disease activity.
It was a case-control study conducted in Beni-Suef University Hospital at outpatient and inpatient Rheumatology and Rehabilitation Department. The study included 50 clinically diagnosed SLE patients and(25) healthy adults served as a control group.
All the seventy individuals included in the study was subjected to a written informed consent for participation in the study, detailed history taking, clinical assessment and Rheumatologic examination. Detection of IL37 level was done by ELISA technique.
The collected data were coded then entered and analyzed taking
three months using the SPSS version 22.
The study revealed that the average age of patients with SLE was
27.48 ±9.6 (SD) years. Sex distribution of studied population; of the studied SLE cases; 88% of them were females and 12% were males.
The serum levels of il-37 in patients with systemic lupus erythematosus (SLE) was higher as compared to normal control persons; however the difference between the two groups was not statistically significant where the p-value >0.05.