الفهرس 
Antipsychotic DrugsOnly 14 pages are availabe for public view
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Abstract
Antipsychotic drugs have unique efficacy in the treatment of psychosis and are approved for treating schizophrenia, bipolar disorder, behavioural and psychiatric symptoms of dementia and depression. Acute antipsychotic drugs poisoning represents one fifth the number of people who commits suicide. Intravenous lipid emulsions (ILE) were developed many decades ago as a source of essential fatty acids to supply nutritional requirements in case of failed enteral feeding. Recently, ILE has been used as an antidote for drug toxicity such as systemic toxicity of local anaesthetics. The increased incidence of acute antipsychotics poisoning, and its high morbidity are real challenge for health care professionals. Unfortunately, there is no specific antidote for antipsychotic overdose and its treatment is mainly supportive and symptomatic. Hence, evaluation of new treatment modalities is necessary to decrease the rate of morbidity and/or mortality. Therefore, the aim of this study was to evaluate the potential efficacy and safety of IV lipid emulsion as an adjuvant therapy for acute antipsychotics poisoning. The present study was conducted on 40 patients presented with moderate to severe acute antipsychotic drugs poisoning. The patients were recruited from the TUPCC, Emergency Hospital, Tanta University, from the start of March 2019 to the end of February 2020.