الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Androgenetic alopecia (AGA) is a non-scarring disease with a progressive thinning of the scalp hair that follows a characteristic pattern. It is the most common form of alopecia, affecting up to 80% of men and 50% of women in the course of their life. Objectives: The aim of this study is to evaluate the possible clinical benefit of lyophilized platelet derived growth factors(L-GF) locally injected in cases of AGA. Patients and Methods: The present pilot study included 20 female patients with AGA. Patients were recruited from the outpatient clinic of Ain Shams University Hospital, in the period at the period from September 2018 till March 2019. The study was approved by the Research Ethical Committee, Faculty of Medicine, Ain Shams University and fulfilled all the ethical aspects required in human research. Results: Treatment with L-GF resulted in improvement of AGA patients with minimal side effects. Conclusion: Lyophilized platelet derived growth factors (L-GF) injection for AGA could represent new therapeutic option for delivering platelet growth factors. As a pilot study, the sample size of this work was small, despite the fact that we had statistical significant results. Further randomized wide scale comparative studies between conventional autologous PRP and L-GF are demanding to draw concrete results. |