الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 151 |  |  |
| | | from | 151 | | |
Abstract
neonatal intensive care Dissertation AbstractIntroduction: Ventilator associated pneumonia (VAP) is one of the most common nosocomial infections in critical care medicine and accounts for 6.8% to 32.2% of nosocomial infections among neonates. It is associated with prolonged hospitalization, increased health care costs, and high attributable mortality.Aim of this study: To evaluate effectiveness of scheduled oral hygiene bundle in control of ventilator-associated pneumonia (VAP) in ventilated preterm infants in NICU and evaluate the efficacy of Mothers’ own milk as a safe oral care product in ventilated preterm infants.Patients and methods: Preterm infants < 34 weeks who needed mechanical ventilation for ≥ 48 h in the first week of life. The targeted sample was 112 infants per group (n=112) Infants allocated in group 1 received oral hygiene bundle. Infants allocated in group 2 received oral care with sterile water on a sterile cotton swab.Methods: Infants allocated in group 1 received oral hygiene bundle that included: applying oral care with scheduled hands-on care every 3-4 h; gentle scrubbing of target known regions for bacterial proliferation; assessment of oral tissue, tongue, saliva, ET and OG; using water-soluble moisturizer/sterile water for lips and gums and oral care with mothers’ own milk every 4 hours until the infant can be weaned from MV. Infants allocated in group 2 received oral care with sterile water on a sterile cotton swab. The two groups were followed up and were assessed for VAP prevalence.Results: Our study proved that oral care with mothers’ own milk is a beneficial preventive strategy to prevent ventilator associated pneumonia (VAP) in NICU (p value <0.001) and proved that mothers’ own milk decrease the incidence of sepsis significantly (p value 0.02) and decrease mortality in preterm infants (p value 0.001).